| Individual/Entity | Most Recent Trans. | Shares Owned as of Trans. Date |
|---|
14159 CAPITAL (GP), LLC
Beneficial Owner (10% or more) | Ownership Statement
06-Mar-2012 | 360,231
06-Mar-2012 | 14159, L.P.
Director | Ownership Statement
19-Jul-2012 | 360,231
19-Jul-2012 | 667, L.P.
Director | Ownership Statement
19-Jul-2012 | 1,585,591
19-Jul-2012 | BAKER BIOTECH CAPITAL (GP), LLC
Beneficial Owner (10% or more) | Ownership Statement
06-Mar-2012 | 1,585,591
06-Mar-2012 | BAKER BROS ADVISORS LLC
Beneficial Owner (10% or more) | Ownership Statement
12-Apr-2012 | 0
12-Apr-2012 | BAKER BROTHERS LIFE SCIENCES CAPITAL (GP), LLC
Beneficial Owner (10% or more) | Ownership Statement
06-Mar-2012 | 13,606,093
06-Mar-2012 | BAKER BROTHERS LIFE SCIENCES LP
Director | Ownership Statement
19-Jul-2012 | 13,606,093
19-Jul-2012 | BAKER JULIAN
Director | Purchase
29-Oct-2012 | 17,888,512
29-Oct-2012 | BOWES WILLIAM K JR
Director | Option Exercise
13-Nov-2012 | 5,570
13-Nov-2012 | KURLAND FRED
Officer | Sale
14-Nov-2012 | 13,485
14-Nov-2012 | NEU KELVIN
Director | Acquisition (Non Open Market)
19-Jul-2012 | 16,800
19-Jul-2012 | RUBIN PAUL D
Officer | Automatic Sale
18-Apr-2013 | 8,749
18-Apr-2013 | SCANNON PATRICK J MD PHD
Officer | Option Exercise
14-May-2013 | 17,448
14-May-2013 | VAN NESS W DENMAN
Director | Option Exercise
13-Nov-2012 | 6,876
13-Nov-2012 | VARIAN JOHN
Officer | Option Exercise
15-May-2013 | 60,079
15-May-2013 | WALBERT TIMOTHY P
Director | Option Exercise
13-Nov-2012 | 4,499
13-Nov-2012 | WYSZOMIERSKI JACK L
Director | Option Exercise
13-Nov-2012 | 4,499
13-Nov-2012 |
|
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